1. Involvement of the Penta-EF-Hand Protein Pef1p in the Ca2+- ... - PLOS
Arrows indicate the critical calcium interacting residues E180, E181, and E248. ... Transition of Sar1p from the GTP-bound to the GDP-bound state was monitored by ...
Although it is well established that the coat protein complex II (COPII) mediates the transport of proteins and lipids from the endoplasmic reticulum (ER) to the Golgi apparatus, the regulation of the vesicular transport event and the mechanisms that act to counterbalance the vesicle flow between the ER and Golgi are poorly understood. In this study, we present data indicating that the penta-EF-hand Ca2+-binding protein Pef1p directly interacts with the COPII coat subunit Sec31p and regulates COPII assembly in Saccharomyces cerevisiae. ALG-2, a mammalian hom*olog of Pef1p, has been shown to interact with Sec31A in a Ca2+-dependent manner and to have a role in stabilizing the association of the Sec13/31 complex with the membrane. However, Pef1p displayed reversed Ca2+ dependence for Sec13/31p association; only the Ca2+-free form of Pef1p bound to the Sec13/31p complex. In addition, the influence on COPII coat assembly also appeared to be reversed; Pef1p binding acted as a kinetic inhibitor to delay Sec13/31p recruitment. Our results provide further evidence for a linkage between Ca2+-dependent signaling and ER-to-Golgi trafficking, but its mechanism of action in yeast seems to be different from the mechanism reported for its mammalian hom*olog ALG-2.
2. Egypt attracts foreign investment as currency falls - Financial Times
Mar 22, 2017 · Egypt is grappling with a budget deficit that reached 12.2 per cent of gross domestic product ... Domestic debt is high at 95 per cent of GDP. The ...
After a radical reform, investors are returning, but can Cairo stay the course?
3. Ectopic expression of eIF2Bε in rat skeletal muscle rescues the sepsis ...
The rate of exchange of [3H]GDP for unlabeled GDP was calculated as the linear decrease in radioactivity captured on nitrocellulose filters (i.e., bound to eIF2) ...
Eukaryotic initiation factor 2B (eIF2B) is a guanine nucleotide exchange factor (GEF) whose activity is both tightly regulated and rate-controlling with regard to global rates of protein synthesis. Skeletal muscle eIF2B activity and expression of its ...
4. [PDF] Appendix A Purchasing Power of the Canadian Dollar - Bank of Canada
gross domestic product (GDP) deflator, is available back to 1870 (Leacy 1983). While the CPI and GDP deflator can diverge, they tend to move together over ...
5. [PDF] Master Builders Australia Submission to the Senate Education and ...
Feb 5, 2021 · Represents about 11% of GDP, the second largest sector within the economy;. ▫. Trains more than one third of the total number of trades-based ...
6. [PDF] Sports Coaching Through the Ages with an Empirical Study of ...
Apr 5, 2013 · about 1% of the annual GDP was allocated to sports for their twenty year, totaling 409. Olympic medals haul over 5 Olympics between 1968 and ...
7. GDP and spending - Gross domestic product (GDP) - OECD Data
Missing: e248 | Show results with:e248
Find, compare and share OECD data by indicator.
8. International socioeconomic inequality drives trade patterns in the global ...
May 5, 2021 · ... GDP and per capita GDP of nations/territories. Both our network ... 2, e248 (2020). [Google Scholar]. 54. Kohler F., Holland T. G., Kotiaho ...
Wealth inequality between nations influences patterns in the international wildlife trade.The wildlife trade is a major cause of species loss and a pathway for disease transmission. Socioeconomic drivers of the wildlife trade are influential at the local ...
9. [PDF] Egypt's IMF Program: Assessing the Political Economy Challenges
content/083a15cc-e248-11e6-9645-c9357a75844a. 14 IMF, “Arab ... 53 Mohamed Hamama, “Sisi Says Military Economy is 1.5% of Egypt's GDP, But How Accurate Is This?
10. UAE bankruptcy no longer leads straight to prison - Financial Times
Mar 22, 2017 · The government's ambition is to boost the contribution of SMEs to GDP from 40 per cent now to 45 per cent in 2021. It hopes to foster 40,000 ...
A new insolvency law will help SMEs caught in a cash crunch
11. A Rational Economic Model of Paygo Tax Rates
... GDP, real wages and the real return to capital since 1950. With uniform risk ... e248-4dc9-aac8-f, Tilburg University, School of Economics and Management ...
We argue that paygo rates are determined by a representative agent and a benevolent government jointly maximizing the expected life-time utility of the agent. The distributions of labor and capital in
12. [PDF] The Importance of Being Marginal: Gender Differences in Generosity
Indeed, since 1971 individual contributions to charitable causes have increased from roughly $130 billion to nearly $300 billion, or about 2% of GDP.
13. [PDF] NBAA President Ed Bolen Testimony, House TI Hearing, FAA ...
Feb 7, 2023 · gross domestic product. Considering the vast challenges facing the FAA ... 64(4):e245-e248. 11. Page 12. aiding employers in understanding the ...
14. FAIR AND ACCURATE CREDIT TRANSACTIONS ACT OF 2003
243 Spriggs, William E........................................... 248 Taylor ... GDP. Since 1970, access to credit has greatly expanded as well. Thirty years ...
15. BGC0002040 - MIBiG
E-value: 2.4e-248. F7Q99_03110. F7Q99_03110 ... GDP-L-fucose synthase. Location: 3225 - 2248. GA0070558_12445. GA0070558_12445
BGC0002040: coformycin biosynthetic gene cluster from Streptomyces kaniharaensis
16. Mark Ashworth | King's College London
GDP, CPI, RPI, and GPs: why economic indicators matter for GPs · L'Esperance ... e241-e248. Research output: Contribution to journal › Article › peer-review ...
Professor of Primary Care
17. [PDF] Analysis of Factors Determining Global Payment Imbalances in ...
Nov 2, 2021 · balance was between -3% GDP and 3% GDP were considered to be in relative balance ... value 1.1454e-248. A low p-value counts against the null.
18. [PDF] Estimating the money flow in the economy attributed to rotavirus ...
Nov 22, 2019 · ciated with considerable loss of gross domestic product (GDP). ... 2018;37(9):e248–50. PubMed. PMID: 00006454-201809000-00027. 39. Stuttard N ...
19. [XLS] Hoja1 - PeerJ
3.0e-248, 72.0, VFG012104 (fbpA) fibronectin-binding protein ... VFG019781 (PLES_19091) UDP-glucose/GDP-mannose dehydrogenase-like protein LPS O-antigen (P.
PK ! bîh^ [Content_Types].xml ¢( ¬ËNÃ0E÷HüCä-Jܲ@5íÇ*Q>ÀÄƪc[iiÿûB¡j7±ÏÜ{2ñÍh²nm¶Æ»RÈÀU^7/ÅÇì%¿rZYï @1__f q·ÃR4DáAJ¬h>ãÚÇVßƹªZ¨9ÈÛÁàNVÞ8Ê©ÓãÑÔji){^óã-I"{Üv^¥P!XS)bR¹rúK¾s(¸3Õ`cÞ0½ÝÎß»¾7M4²©ôªZÆk+¿|\|z¿(ôPúº6h_-[@!ÒØ Pk´2nÏ}Ä?£LËð Ýû%áÄßdºdN"m,à¥ÇDO97*~§Èɸ8ÀOíc|n¦ÑäEøÿöéºóÀBÉÀ!$}íàÈé;{ìÐå[îñé2þ ÿÿ PK ! µU0#ô L _rels/.rels ¢( ¬MOÃ0ïHüÈ÷ÕÝBKwAH»!T~Iܵ£$Ý¿'TG½~üÊÛÝ<êÈ!öâ4¬;#¶wúqu*&rFq¬áÄvÕõÕöGJy(v½*...
20. https://www.mdc-berlin.de/media/16725
... e-248 NA NA 0 A2AEW8;Q8VD04;A2AEW9;A2AEW5 A2AEW8;Q8VD04;A2AEW9;A2AEW5 25;25;23 ... GDP-GTP exchange factor subunit delta;Translation initiation factor eIF-2B ...
Protein.IDs Majority.Protein.IDs Peptide.Counts..all. Peptide.Counts..razor.unique. Peptide.Counts..unique. Protein.Names Uniprot Razor...unique.Peptides Unique.Peptides Peptides Razor...unique.Peptides.D_L4ctr_L0_280 Razor...unique.Peptides.S_L0ctr_L4_580 Sequence.Coverage.... Mol..Weight..kDa. Sequence.Length Experiment PEP Ratio.H.L Ratio.H.L.Normalized Intensity Reverse Contaminant A0ELI5;Q8K2D3;D3YYS4;D6RCX6 A0ELI5;Q8K2D3 5;5;1;1 5;5;1;1 5;5;1;1 Putative uncharacterized protein;Enhancer of mRNA-decapping protein 3;YjeF domain-containing protein 1 A0ELI5 5 5 1 2 0 14.6 55.957 508 2 1.7845e-08 NA NA 198470000 A0JNY3;Q8BUV3 A0JNY3;Q8BUV3 12;12 12;12 12;12 Gphn protein;Domain E;Domain G;Gephyrin;Molybdopterin adenylyltransferase;Molybdopterin molybdenumtransferase A0JNY3 12 12 2 3 2 19.2 83.665 772 4 4.7642e-82 0.78404 1.0635 809120000 A0MNP4;Q9ERF3;Q8BVQ0;F6U7Z8 A0MNP4;Q9ERF3;Q8BVQ0;F6U7Z8 6;6;6;5 6;6;6;5 6;6;6;5 CDW13/WDR61;WD repeat domain 61, isoform CRA_c;Meiotic recombination REC14 protein hom*olog;WD repeat-containing protein 61;Putative uncharacterized protein A0MNP4 6 6 2 1 2 35.7 33.772 305 6 2.1838e-85 0.70994 0.97035 235010000 A0PK78;Q78PG9 A0PK78;Q78PG9 6;6 6;6 6;6 Coiled-coil domain containing 25;Coiled-coil domain-containing protein 25 A0PK78 6 6 2 0 4 31.2 24.48 208 2 5.9107e-22 0.42715 0.58119 318090000 A1A4T2;Q8BHN3-2;Q8BHN3;Q8BHN3-3 A1A4T2;Q8BHN3-2;Q8BHN3 8;8;8;2 8;8;8;2 8;8;8;2 Alpha glucosidase 2 alpha neutral subunit;Alpha glucosidase 2 alph...
